I've only read book one, so I can't comment about everything, but I've been thinking a little bit...
Looking at VegasDev's idea above, tbh, I don't really like them, the sound to me like far too little control, a limitation of oneor perhaps two total pushes and pulls at a time, pushing an pulling by pointing in a general direction and the game engine deciding if there's anything their rather than selecting blue threads, it just seems like an underselling of the book to me.
If I were playing a game based on mistborn, I would want to be able to choose which metals to burn at all times, having to manage metal stocks would be interesting.
As for control schemes, I think that to use iron and steel, you'd need some kind of pointer to select which thread, any other method would be clunky in my opinion, this rules out the 360 and the ps3 as they have no pointer, so, it's either the Wii or a Computer (a mouse would make a fine pointer). I mention the Wii, but, I'm not sure if it would have the power to handle the type of game fans of this book would want, the ability to push and pull on any metal object would be a must as would fights involving multiple mistborns and many mistings, these would get very complicated, in addition to this, I don't think the Wii (or any other console) would have enough buttons to handle weapons of varying kinds, (coins, knifes, stuff off of the ground, vials of metal), and all of the allomancy at the same time.
Therefore, I think that realistically it would have to be a computer game. Number keys trigger metals on/off, when burning iron/steel, you could use the mouse as a pointer, left click = push, right click = pull. (even this wouldn't be perfect, as you should be able to push on one thing while pulling on another, or even push on ten things while pulling on ten other things), I guess you could start pulling on something by left clicking on it's blue thread, and stop pulling on it by clicking on it again, but for something like that to work, you'd probably need slow motion, perhaps some kind of level up system, with the higher the level you reach the slower you can make the action run, of course this wouldn't wok for multiplayer.
I wouldn't want atium to change game speed much if at all, I'd just want the shadows to appear, and it would be a case of reacting to what you see.
Anyway, I'm a 17 year old who's dabbled slightly in amateur game making, I don't have a team, I don't have the skill, I don't have the time and I don't have the equipment to make anything like what I've just described., if I were to make something it would have to be 2d, and would therefore be absolutely rubbish compared to what it should be.